Endocrine Abstracts

Objectives: Neurogenetical predictors of psychological disturbances in children with severe obesity.Methods: We examined 254 pubertal obese children: group1 (simple obesity) 187 children, 14.3±2.0 yrs, 30.4±2.8 kg/m2; group2 (severe obesity) 67 children, 14.7±2.1, 39.1±3.8. Control 80 children, 14.4±2.0 yrs, 19.7±1.7 kg/m2. Dopamine levels were determined. Genotyping was performed on polymorphic genes C...

Background: It is well known that many nuerohormonal and genetic factors influence on the developing of obesity in children. Serotoninergic system is determined to be one of the most important factors. Serotonin may induce lipogenesis or triacylglycerol synthesis in the liver and/or white adipose tissue.Aim: To establish interactions between serotoninergic system and metabolic parameters in obese children.Methods: We examined 280 c...

Background: Social adaptation difficulty is one of the serious complications in obese children. It manifests with the complex of emotional and behavioral disorders.Aim: To estimate the peculiarities of psychological status, frequency, and severity of depressive disorders in obese children.Methods: We examined 242 children in the in the Endocrinological Department of University Hospital (Minsk); group 1 – 152 obese children (BM...

Background: Binge eating (BE) is a common cause of severe paediatric obesity, which develops after the uncontrolled wish of changing the present emotional condition.Aim: To study the phenomenon of BE in the context of emotional disorders in severe obese children.Methods: We examined 88 children with severe obesity (mean±s.d. 11.5±3.4 years; BMI 29.7±5.7 kg/m2) in the Endocrinological Department of Universi...